2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. Neurotensin Receptor
  5. Neurotensin Receptor Activator

Neurotensin Receptor Activator

Neurotensin Receptor Isoform Comparison

Neurotensin Receptor Activators (2):

Cat. No. Product Name Effect Purity
  • HY-P2544
    [Lys8, Lys9]-Neurotensin (8-13)
    		Activator 99.98%
    [Lys8, Lys9]-Neurotensin (8-13) (JMV438), a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, with Ki values of 0.33 nM and 0.95 nM for hNTS1 and hNTS2 receptors, respectively.
  • HY-P10767
    MD01-67
    		Activator
    MD01-67 is a selective macrocyclic compound targeting the neurotensin receptor type 2 (NTS2), with Ki of 2.9 nM. MD01-67 exhibits analgesic and tactile hypersensitivity reducing activity in rats acute/persistent/chronic inflammatory pain models.